I did my PhD from Indian Institute of Chemical Biology, Kolkata under the supervision of Dr. Krishnananda Chattopadhyay. During my PhD, we showed how the ultra-fast chain dynamics of protein can be monitored at a single molecular resolution. After that, I moved to Max Planck Institute of Biochemistry and started working with Prof. Ulrich Hartl. During my postdoc in Munich, we solved the mechanism of the most important bacterial chaperonin, GroEL-GroES.
I joined the lab in March 2016, I will use force spectroscopy techniques such as magnetic tweezers and AFM to study the folding dynamics of the giant elastic muscle protein Titin and its contribution to muscle contraction. In particular, my studies will focus on the role of chaperones on promoting Titin folding and increasing the strength of a muscle contraction