Julio M. Fernandez
Much of what is known about protein dynamics has been studied using bulk biochemical techniques and chemical denaturants. By contrast, we study proteins at the single molecule level and use mechanical forces to denature proteins. Force is a ubiquitous denaturant in biology. Our results are opening new vistas into protein function and challenging some widely accepted views of protein dynamics.
Courses taught at Columbia University:
- Frontiers of Science, Science C1000
- The Biology and Physics of Single Molecules, Biology Biology W4070
- Cellular Physiology of Disease, Biology W3008/W4008
- Student evaluations: Dr. Fernandez is the BEST professor I have had a Columbia, hands down. I wish I had met him my first year here; Best Biology professor that I've ever encountered at Columbia. Very rare find! He is very clear and available for questions, and I've enjoyed going to office hours; Really wonderful teacher who genuinely wants his students to be as fascinated with the material as he is.
Research stats:153 publications, 18165 citations, h index=67 (Jan 2014)
Ambition: revolutionize protein biochemistry through the use of single molecule force-spectroscopy.