Jaime Andres Rivas Pardo
I obtained my PhD in 2012 from University of Chile (Santiago, Chile) under the supervision of Dr. Victoria Guixe, at the Biological Sciences Department. My work there was related to understanding the conformational changes that thermophilic proteins undergo in solution. We used different techniques to determine the kinetic mechanisms and biophysical properties of glycolytic enzymes from hyperthermophilic organisms.
I joined the lab in September 2012, with the intent of studying protein conformational transition but this time at single molecule level. I currently use the enzyme glucokinase as a model to study the transition triggered by ligand from the Open to the Closed conformation. Also, I am involved in several projects with different members of Professor Fernandez's lab, trying to understand the function of posttranslational modifications on folding pathways of mechanical proteins.